Lorenzo Mattott was born in Brescia (Lombardy). He studied architecture when he was young, but did not finish the course. Instead he became a comics artist. After a few traditional comic stories he decided he wanted to tell different kinds of stories and portray these in a different style. His debut as a film director was a segment in the animated horror anthology Fear(s) of the Dark, released in 2007. His first feature film is the “The Bears' Famous Invasion of Sicily”, which premiered at the Cannes Film Festival 2019. The film is an animated adaptation of Dino Buzzati's 1945 children's book of the same title.